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Home / Proteins & Peptide

Recombinant Human MEK5 (N-GST tag)

SKU : BHP10900166

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Applied Biological Materials (abm) Inc.

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Mfr.No.	Z500216
Description	MEK5 or MAP2K5 (mitogen-activated protein kinase kinase 5) is a dual specificity protein kinase that belongs to the MAP kinase kinase family which specifically interacts with and activates MAPK7/ERK5. MEK5 itself can be phosphorylated and activated by MAP3K3/MEKK3, as well as by atypical protein kinase C isoforms (aPKCs). The signal cascade mediated by MEK5 is involved in growth factor stimulated cell proliferation and muscle cell differentiation . The rs3743354 polymorphism in the MEK5 promoter may affect the risk of developing colorectal cancer (CRC) .
Alternative Names	MKK5 ; PRKMK5 ; SAPKK5 ; SKK5 ; HsT17454 ; MAP2K5 ; MAPKK5
Tag	N-GST tag
Quantity	10 µg
Regulatory	RUO
Source	Insect cells
Host	Human
Biological Activity Comment	The specific activity of MEK5 was determined to be 85nmol /min/mg as per activity assay protocol.

Weight	77.0 kDa

Format	Liquid 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.
Purity	70% - 90%
Storage	Store product at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.

Immunogen Species	Homo Sapiens (Human)

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SKU	Supplier No.	Size	Your price	Quantity
BHP10900166	Z500216	10µg	$361.11		Add to Cart

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