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Recombinant Human Lysine-specific demethylase 3B(KDM3B) ,partial

SKU : BHP10504785

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-EP759174HU
Description	Histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a central role in histone code. Demethylation of Lys residue generates formaldehyde and succinate. May have tumor suppressor activity.
Alternative Names	JmjC domain-containing histone demethylation protein 2B, Jumonji domain-containing protein 1B, Nuclear protein 5qNCA, JmjC domain-containing histone demethylation protein 2B Jumonji domain-containing protein 1B Nuclear protein 5qNCA
Tag	N-terminal 10xHis-SUMO-tagged and C-terminal Myc-tagged
Regulatory	RUO
Relevance	Histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a central role in histone code. Demethylation of Lys residue generates formaldehyde and succinate. May have tumor suppressor activity.
Source	E.coli
Abbreviation	KDM3B
Notes	Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Protein Name	Recommended name: Lysine-specific demethylase 3B; EC= 1.14.11.-; Alternative name(s): JmjC domain-containing histone demethylation protein 2B; Jumonji domain-containing protein 1B; Nuclear protein 5qNCA
Expression Region	1498-1721aa
Mol Weight	45.6kDa
Nature	Recombinant
Protein Description	Partial

Subcellular Location	Nucleus
Uniprot	Q7LBC6, Q7LBC6
Database Links	HGNC:1337 OMIM:609373 KEGG:hsa:51780 STRING:9606.ENSP00000326563 UniGene:Hs.483486
Function	Histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a central role in histone code. Demethylation of Lys residue generates formaldehyde and succinate. May have tumor suppressor activity.
Protein Families	JHDM2 histone demethylase family
Research Area	Epigenetics and Nuclear Signaling
Tissue Specificity	Ubiquitous. Highly expressed in placenta, skeletal muscle, kidney, heart and liver.
Weight	45.6 kDa

Stotage Note	Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.
Buffer	Tris-based buffer，50% glycerol
Purity	Greater than 90% as determined by SDS-PAGE.
Storage	The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Storage Buffer	Tris-based buffer,50% glycerol

Immunogen Species	Homo Sapiens (Human)

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SKU	Supplier No.	Size	Your price	Quantity
BHP10504785	CSB-EP759174HU	1mg	$1812		Add to Cart
BHP10504785	CSB-EP759174HU	100ug	$419		Add to Cart
BHP10504785	CSB-EP759174HU	20ug	$224		Add to Cart

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