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Home / Proteins & Peptide

Recombinant Human Leukosialin(SPN),partial

SKU : BHP10500941

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-EP022590HU
Alternative Names	Galactoglycoprotein ,GALGPLeukocyte sialoglycoprotein,Sialophorin, CD43, Galactoglycoprotein ; GALGPLeukocyte sialoglycoprotein ; Sialophorin ; CD43
Antigen	SPN
Tag	N-terminal 6xHis-SUMO-tagged
Regulatory	RUO
Relevance	One of the major glycoproteins of thymocytes and T lymphocytes. Plays a role in the physicochical properties of the T-cell surface and in lectin binding. Presents carbohydrate ligands to selectins. Has an extended rodlike structure that could protrude above the glycocalyx of the cell and allow multiple glycan chains to be accessible for binding. Is a counter-receptor for SN/Siglec-1 . During T-cell activation is actively roved from the T-cell-APC (antigen-presenting cell) contact site thus suggesting a negative regulatory role in adaptive immune response .
Source	E.coli
Notes	Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Expression Region	20-253aa
Mol Weight	39.5kDa
Nature	recombinant
Protein Description	Partial

Subcellular Location	Membrane, Single-pass type I membrane protein
Uniprot	P16150, P16150
Database Links	HGNC:11249 OMIM:182160 KEGG:hsa:6693 STRING:9606.ENSP00000353238 UniGene:Hs.632188
Function	One of the major glycoproteins of thymocytes and T lymphocytes. Plays a role in the physicochemical properties of the T-cell surface and in lectin binding. Presents carbohydrate ligands to selectins. Has an extended rodlike structure that could protrude above the glycocalyx of the cell and allow multiple glycan chains to be accessible for binding. Is a counter-receptor for SN/Siglec-1 (By similarity). During T-cell activation is actively removed from the T-cell-APC (antigen-presenting cell) contact site thus suggesting a negative regulatory role in adaptive immune response (By similarity).
Research Area	Immunology
Tissue Specificity	Cell surface of thymocytes, T-lymphocytes, neutrophils, plasma cells and myelomas.
Weight	39.44kDa

Stotage Note	Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.
Buffer	Tris-based buffer，50% glycerol
Purity	Greater than 90% as determined by SDS-PAGE.
Storage	The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Storage Buffer	Tris-based buffer,50% glycerol

Immunogen Species	Homo Sapiens (Human)

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SKU	Supplier No.	Size	Your price	Quantity
BHP10500941	CSB-EP022590HU	1mg	$1812		Add to Cart
BHP10500941	CSB-EP022590HU	100ug	$419		Add to Cart
BHP10500941	CSB-EP022590HU	20ug	$224		Add to Cart

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