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Recombinant Human Leptin protein(LEP) (Active)

BHP10500248
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Contact us to order
Tel
+1 866.986.9598
Email
[email protected]
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Involvement In Disease Leptin deficiency (LEPD)
Subcellular Location Secreted
Uniprot P41159, P41159
Database Links

HGNC:6553

OMIM:164160

KEGG:hsa:3952

STRING:9606.ENSP00000312652

UniGene:Hs.194236
Function Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways
Pathway Jak-STAT signaling pathway; Adipocytokine signaling pathway; AMPK signaling
Protein Families Leptin family
Research Area Signal Transduction
Tissue Specificity Adipose tissue is the main source of leptin it is also produced by other peripheral tissues such as the skeletal muscle (PubMed:7789654, PubMed:16052473, PubMed:12448771). Expressed by intercalated and striated tracts of submandibular and parotid salivary
Weight 16.0 kDa
Buffer 0.2 µm filtered PBS, pH 7.4,lyophilized
Purity >97% as determined by SDS-PAGE and HPLC.
Storage Buffer 0.2 μm filtered PBS, pH 7.4 ,lyophilized
Immunogen Species Homo Sapiens (Human)
SKU Supplier No. Size Your price Quantity
BHP10500248 CSB-AP000061HU 200ug $128
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