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Home / Proteins & Peptide

Recombinant Human LAMTOR2/ROBLD3/MAPBPIP Protein (His Tag)

SKU : BHP10300372

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Elabscience Biotechnology Co.,Ltd

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Mfr.No.	PKSH030802
Description	A DNA sequence encoding the mature form of human LAMTOR2 isoform 1 (Q9Y2Q5-1) (Met 1-Ser 125) was expressed, with a polyhistide tag at the N-terminus.
Alternative Names	LAMTOR2 ; RP11-336K24.9 ; ENDAP ; HSPC003 ; MAPBPIP ; MAPKSP1AP ; ROBLD3 ; Ragulator2 ; p14
Background	Ragulator complex protein LAMTOR2, also known as Endosomal adaptor protein p14, Late endosomal/ lysosomal Mp1-interacting protein, Late endosomal/ lysosomal adaptor and MAPK and MTOR activator 2, Mitogen-activated protein-binding protein-interacting protein, Roadblock domain-containing protein 3, LAMTOR2, MAPBPIP and ROBLD3, is a protein which belongs to the GAMAD family. LAMTOR2/ ROBLD3 is a regulator of the TOR pathway, a signaling cascade that promotes cell growth in response to growth factors, energy levels, and amino acids. As part of the Ragulator complex, LAMTOR2/ ROBLD3 recruits the Rag GTPases and the mTORC1 complex to lysosomes, a key step in activation of the TOR signaling cascade by amino acids. LAMTOR2/ ROBLD3 is an adapter protein that enhances the efficiency of the MAP kinase cascade facilitating the activation of MAPK2. Defects in LAMTOR2 are the cause of immunodeficiency due to defect in MAPBP-interacting protein (ID-MAPBPIP). This form of primary immunodeficiency syndrome includes congenital neutropenia, partial albinism, short stature and B-cell and cytotoxic T-cell deficiency.
Tag	His tag
Regulatory	RUO
Host	E. coli
Nature	Recombinant

Shipping	In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
Buffer	Lyophilized from sterile PBS, pH 7.4
Description	Please refer to the printed manual for detailed information.
Purity	> 97 % as determined by SDS-PAGE
Expiry Date	Samples are stable for up to twelve months from date of receipt at -70℃

Immunogen Species	Homo Sapiens (Human)

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SKU	Supplier No.	Size	Your price	Quantity
BHP10300372	PKSH030802	100ug	$855		Add to Cart

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