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Home / Proteins & Peptide

Recombinant Human LAIR2/CD306 Protein (His Tag)(Active)

SKU : BHP10302946

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Elabscience Biotechnology Co.,Ltd

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Mfr.No.	PKSH031383
Description	A DNA sequence encoding the human LAIR2 (NP_002279.2) (Met 1-Pro 152) with a C-terminal polyhistidine tag was expressed.
Alternative Names	Leukocyte-Associated Immunoglobulin-Like Receptor 2; LAIR-2; CD306; LAIR2
Reconstitution	Please refer to the printed manual for detailed information.
Background	Leukocyte-associated immunoglobulin-like receptor 2 ( LAIR2 ), also known as CD306, is a 131 amino acid protein containing one lg-like C2-type domain. It is expressed as a soluble receptor exhibiting high affinity for various collagen molecules to which it binds in a hydroxyproline-dependent manner. LAIR2 is a member of the immunoglobulin superfamily and was identified by its similarity to LAIR1, an inhibitory receptor present on mononuclear leukocytes. LAIR2 is thought to be secreted and may help modulate mucosal tolerance. As a natural competitor for LAIR1, soluble LAIR2 prevents binding of human LAIR1 to collagens and LAIR1 cross-linking, thereby regulating its inhibitory potential. Accordingly, LAIR2 is suggested to perform an immunoregulatory function.
Reactivity	Human
Tag	C-His
Formulation	Lyophilized from sterile PBS, pH 7.4
Host	HEK293 Cells
Accession Number	NP_002279.2
Endotoxin Level	< 1.0 EU per ug as determined by the LAL method.
Bioactivity	Measured by the ability of the immobilized protein to support the adhesion of HT-29 human colon adenocarcinoma cells. When 1 x 10E4 cells/well are added to Recombinant Human LAIR2 coated plates (50 ug/ml with 100 ul/well), approximately >40% cells will adhere after 10 minutes at 37?. Optimal concentration depends on cell type as well as the application or research objectives.
Mol Weight	15.5 kDa
Mw(kda)	15.5 kDa

Sequence Info	Met 1-Pro 152

Shipping	This product is provided as lyophilized powder which is shipped with ice packs.
Stotage Note	Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Purity	> 97 % as determined by reducing SDS-PAGE.

Product Manual	Data Sheet

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SKU	Supplier No.	Size	Your price	Quantity
BHP10302946	PKSH031383	100ug	$732		Add to Cart

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