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Home / Proteins & Peptide

Recombinant Human L-xylulose reductase(DCXR)

SKU : BHP10503801

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-EP772022HU
Alternative Names	Carbonyl reductase II, Dicarbonyl/L-xylulose reductase, Kidney dicarbonyl reductase, Carbonyl reductase II ; Dicarbonyl/L-xylulose reductase ; Kidney dicarbonyl reductase
Tag	N-terminal GST-tagged
Regulatory	RUO
Relevance	Catalyzes the NADPH-dependent reduction of several pentoses, tetroses, trioses, alpha-dicarbonyl compounds and L-xylulose. Participates in the uronate cycle of glucose metabolism. May play a role in the water absorption and cellular osmoregulation in the proximal renal tubules by producing xylitol, an osmolyte, thereby preventing osmolytic stress from occurring in the renal tubules.
Source	E.coli
Abbreviation	DCXR
Notes	Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Protein Name	Recommended name: L-xylulose reductase; Short name= XR; EC= 1.1.1.10; Alteative name(s): Carbonyl reductase II; Dicarbonyl/L-xylulose reductase; Kidney dicarbonyl reductase; Short name= kiDCR; Sperm surface protein P34H
Expression Region	1-244aa
Mol Weight	52.9kDa
Nature	recombinant
Protein Description	Full Length

Involvement In Disease	Pentosuria (PNTSU)
Subcellular Location	Membrane, Peripheral membrane protein
Uniprot	Q7Z4W1, Q7Z4W1
Database Links	HGNC:18985 OMIM:260800 KEGG:hsa:51181 STRING:9606.ENSP00000303356 UniGene:Hs.9857
Function	Catalyzes the NADPH-dependent reduction of several pentoses, tetroses, trioses, alpha-dicarbonyl compounds and L-xylulose. Participates in the uronate cycle of glucose metabolism. May play a role in the water absorption and cellular osmoregulation in the proximal renal tubules by producing xylitol, an osmolyte, thereby preventing osmolytic stress from occurring in the renal tubules.
Protein Families	Short-chain dehydrogenases/reductases (SDR) family
Research Area	Signal Transduction
Tissue Specificity	Highly expressed in kidney, liver and epididymis. In the epididymis, it is mainly expressed in the proximal and distal sections of the corpus region. Weakly or not expressed in brain, lung, heart, spleen and testis.
Weight	54.484kD

Stotage Note	Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.
Buffer	Tris-based buffer，50% glycerol
Purity	Greater than 90% as determined by SDS-PAGE.
Storage	The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Storage Buffer	Tris-based buffer,50% glycerol

Immunogen Species	Homo Sapiens (Human)

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SKU	Supplier No.	Size	Your price	Quantity
BHP10503801	CSB-EP772022HU	1mg	$1812		Add to Cart
BHP10503801	CSB-EP772022HU	100ug	$419		Add to Cart
BHP10503801	CSB-EP772022HU	20ug	$224		Add to Cart

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