KHS1 belongs to serine/threonine kinase family that has a STE20-like protein kinase domain which stimulates the stress-activated protein kinase (SAPK, also known as Jun kinase or JNK) pathway . It is a mitogen-activated protein kinase kinase kinase kinase 5, termed germinal center kinase related (GCKR). Recently, the KH domain of Escherichia coli polynucleotide phosphorylase has been reported to be necessary for autoregulation and growth at low temperature .
Alternative Names
MAP4K5 ; KHS ; GCKR ; MAPKKKK5
Tag
N-GST tag
Quantity
10 µg
Regulatory
RUO
Source
Insect cells
Host
Human
Biological Activity Comment
The specific activity of KHS1 was determined to be 86 nmol /min/mg as per activity assay protocol.
Store product at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.