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Home / Proteins & Peptide

Recombinant Human KGF (FGF7)

SKU : BHP10901105

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Applied Biological Materials (abm) Inc.

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Mfr.No.	Z102727
Description	KGF is a member of the family of fibroblast growth factors, it is secreted in large amounts by fibroblast-like stromal cells in epithelial tissues. The KGF receptor encodes a tyrosine kinase and is a member of the family of receptors binding aFGF and bFGF. Binding of KGF to its receptor is competed by aFGF and bFGF. Although KGF is a potent specific mitogen for many epithelial cells it is not so for fibroblasts and endothelial cells. KGF is thought to play an important role in the paracrine growth control of normal epithelial cells. KGF stimulates the proliferation of primary and secondary human keratinocytes to the same extent as EGF. Recombinant Human FGF7 expressed in human 293 cells is a monomeric glycoprotein with an molecular mass of 17 and 30 kDa.
Alternative Names	KGF ; Fibroblast Growth Factor-7 ; HBGF-7 ; Heparin-binding growth factor 7Recombinant Human Keratinocyte Growth Factor (FGF7)
Quantity	100 µg
Regulatory	RUO
Source	HEK293
Host	Human
Endotoxin Level	<1 EU/µg of recombinant protein as determined by the LAL method
Biological Activity Comment	The EC(50) as determined by the dose-dependent stimulation of the proliferation of 4MBr-5 cells (monkey epithelial cell line) was found to be ≤ 7.5 ng/mL.

Weight	17 and 30 kDa, monomer, glycosylated

Description	A quick spin of the vial followed by reconstitution in sterile 1xPBS.
Format	Lyophilized Powder 1x PBS
Purity	>95% as determined by SDS-PAGE
Storage	The lyophilized protein is stable for at least one year from date of receipt at -70°C. Upon reconstitution, this cytokine can be stored in working aliquots at 2° - 8°C for one month, or at -20°C for six months. Avoid repeated freeze/thaw cycles.

Immunogen Species	Homo Sapiens (Human)

MSDS	Growth Factors, Cytokines & Kinases MSDS
Other	Growth Factor and Cytokine Brochure

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SKU	Supplier No.	Size	Your price	Quantity
BHP10901105	Z102727	100µg	$2100.50		Add to Cart

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