Recombinant Human Keratin, type I cytoskeletal 10(KRT10)

Mfr.No.	CSB-EP012504HU
Alternative Names	Cytokeratin-10 ,CK-10Keratin-10 ,K10, Cytokeratin-10 ; CK-10Keratin-10 ; K10
Tag	N-terminal 6xHis-tagged
Regulatory	RUO
Source	E.coli
Notes	Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Expression Region	1-584aa
Mol Weight	62.8kDa
Nature	recombinant
Protein Description	Full Length

Involvement In Disease	Epidermolytic hyperkeratosis (EHK); Ichthyosis annular epidermolytic (AEI); Erythroderma, ichthyosiform, congenital reticular (CRIE)
Uniprot	P13645, P13645
Database Links	HGNC:6413 OMIM:113800 KEGG:hsa:3858 STRING:9606.ENSP00000269576 UniGene:Hs.99936
Pathway	Estrogen signaling pathway
Protein Families	Intermediate filament family
Research Area	Signal Transduction
Tissue Specificity	Seen in all suprabasal cell layers including stratum corneum.
Weight	62.9kDa

Stotage Note	Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.
Buffer	Tris-based buffer，50% glycerol
Purity	Greater than 90% as determined by SDS-PAGE.
Storage	The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Storage Buffer	Tris-based buffer,50% glycerol