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Home / Proteins & Peptide

Recombinant Human Kallikrein-7(KLK7),partial

SKU : BHP10500677

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-EP012458HU
Alternative Names	Serine protease 6Stratum corneum chymotryptic enzyme ,hSCCE, Serine protease 6Stratum corneum chymotryptic enzyme ; hSCCE
Antigen	KLK7
Tag	N-terminal GST-tagged
Regulatory	RUO
Relevance	May catalyze the degradation of intercellular cohesive structures in the cornified layer of the skin in the continuous shedding of cells from the skin surface. Specific for amino acid residues with aromatic side chains in the P1 position. Cleaves insulin A chain at '14-Tyr- ; -Gln-15' and insulin B chain at '6-Leu- ; -Cys-7', '16-Tyr- ; -Leu-17', '25-Phe- ; -Tyr-26' and '26-Tyr- ; -Thr-27'. Could play a role in the activation of precursors to inflammatory cytokines.
Source	E.coli
Notes	Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Expression Region	28-253aa
Mol Weight	51.7kDa
Nature	recombinant
Protein Description	Full Length of Mature Protein

Subcellular Location	Secreted
Uniprot	P49862, P49862
Database Links	HGNC:6368 OMIM:604438 KEGG:hsa:5650 STRING:9606.ENSP00000375683 UniGene:Hs.151254
Function	May catalyze the degradation of intercellular cohesive structures in the cornified layer of the skin in the continuous shedding of cells from the skin surface. Specific for amino acid residues with aromatic side chains in the P1 position. Cleaves insulin A chain at '14-Tyr- ; -Gln-15' and insulin B chain at '6-Leu- ; -Cys-7', '16-Tyr- ; -Leu-17', '25-Phe- ; -Tyr-26' and '26-Tyr- ; -Thr-27'. Could play a role in the activation of precursors to inflammatory cytokines.
Protein Families	Peptidase S1 family, Kallikrein subfamily
Research Area	Cancer
Tissue Specificity	Abundantly expressed in the skin and is expressed by keratinocytes in the epidermis. Also expressed in the brain, mammary gland, cerebellum, spinal cord and kidney. Lower levels in salivary glands, uterus, thymus, thyroid, placenta, trachea and testis. Up
Weight	55.8kDa

Stotage Note	Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.
Buffer	Tris-based buffer，50% glycerol
Purity	Greater than 90% as determined by SDS-PAGE.
Storage	The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Storage Buffer	Tris-based buffer,50% glycerol

Immunogen Species	Homo Sapiens (Human)

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SKU	Supplier No.	Size	Your price	Quantity
BHP10500677	CSB-EP012458HU	1mg	$1812		Add to Cart
BHP10500677	CSB-EP012458HU	100ug	$419		Add to Cart
BHP10500677	CSB-EP012458HU	20ug	$224		Add to Cart

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