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Home / Proteins & Peptide

Recombinant Human Interleukin-6 receptor subunit alpha(IL6R),partial

SKU : BHP10502794

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-YP011665HU
Alternative Names	Interleukin 6 receptor, isoform CRA_a
Tag	N-terminal 6xHis-tagged
Regulatory	RUO
Relevance	cytokine receptor activity
Source	Yeast
Notes	Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Protein Name	Recommended name: Interleukin-6 receptor subunit alpha Short name= IL-6 receptor subunit alpha Short name= IL-6R subunit alpha Short name= IL-6R-alpha Short name= IL-6RAAlternative name(s): IL-6R 1 Membrane glycopr
Expression Region	20-365aa
Mol Weight	40.5kDa
Nature	recombinant
Protein Description	Partial

Subcellular Location	Isoform 1: Basolateral cell membrane, Single-pass type I membrane protein, SUBCELLULAR LOCATION: Isoform 2: Secreted
Uniprot	A0N0L5, P08887
Database Links	HGNC:6019 OMIM:147880 KEGG:hsa:3570 STRING:9606.ENSP00000357470 UniGene:Hs.135087
Function	Part of the receptor for interleukin 6. Binds to IL6 with low affinity, but does not transduce a signal. Signal activation necessitate an association with IL6ST. Activation may lead to the regulation of the immune response, acute-phase reactions and hematopoiesis.; FUNCTION
Pathway	HIF-1 signaling pathway; Jak-STAT signaling pathway; PI3K-Akt signaling pathway; Hematopoietic cell lineage; Th17 cell differentiation; Inflammatory Pain
Protein Families	Type I cytokine receptor family, Type 3 subfamily
Research Area	Immunology
Tissue Specificity	Isoform 2 is expressed in peripheral blood mononuclear cells and weakly found in urine and serum.
Weight	40.54kDa

Stotage Note	Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.
Buffer	Tris-based buffer，50% glycerol
Purity	Greater than 90% as determined by SDS-PAGE.
Storage	The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Storage Buffer	Tris-based buffer,50% glycerol

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SKU	Supplier No.	Size	Your price	Quantity
BHP10502794	CSB-YP011665HU	500ug	$1298		Add to Cart
BHP10502794	CSB-YP011665HU	100ug	$470		Add to Cart
BHP10502794	CSB-YP011665HU	20ug	$250		Add to Cart

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