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Home / Proteins & Peptide

Recombinant Human Integrin-linked kinase-associated serine/threonine phosphatase 2C(ILKAP)

SKU : BHP10500653

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-EP011686HU
Tag	N-terminal 6xHis-SUMO-tagged
Regulatory	RUO
Relevance	Protein phosphatase that may play a role in regulation of cell cycle progression via dephosphorylation of its substrates whose appropriate phosphorylation states might be crucial for cell proliferation. Selectively associates with integrin linked kinase (ILK), to modulate cell adhesion and growth factor signaling. Inhibits the ILK-GSK3B signaling axis and may play an important role in inhibiting oncogenic transformation.
Source	E.coli
Notes	Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Expression Region	1-392aa
Mol Weight	58.9kDa
Nature	recombinant
Protein Description	Full Length

Subcellular Location	Cytoplasm
Uniprot	Q9H0C8, Q9H0C8
Database Links	HGNC:15566 KEGG:hsa:80895 STRING:9606.ENSP00000254654 UniGene:Hs.92033
Function	Protein phosphatase that may play a role in regulation of cell cycle progression via dephosphorylation of its substrates whose appropriate phosphorylation states might be crucial for cell proliferation. Selectively associates with integrin linked kinase (ILK), to modulate cell adhesion and growth factor signaling. Inhibits the ILK-GSK3B signaling axis and may play an important role in inhibiting oncogenic transformation.
Protein Families	PP2C family
Research Area	Signal Transduction
Tissue Specificity	Widely expressed. Highest levels expressed in striated muscle. Much lower levels evident in various smooth muscle tissues.
Weight	58.9kDa

Stotage Note	Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.
Buffer	Tris-based buffer，50% glycerol
Purity	Greater than 90% as determined by SDS-PAGE.
Storage	The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Storage Buffer	Tris-based buffer,50% glycerol

Immunogen Species	Homo Sapiens (Human)

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SKU	Supplier No.	Size	Your price	Quantity
BHP10500653	CSB-EP011686HU	1mg	$1812		Add to Cart
BHP10500653	CSB-EP011686HU	100ug	$419		Add to Cart
BHP10500653	CSB-EP011686HU	20ug	$224		Add to Cart

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