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Home / Proteins & Peptide

Recombinant Human Insulin-like growth factor-binding protein 5 protein(IGFBP5) (Active)

SKU : BHP10500184

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-AP002501HU
Alternative Names	IBP-5, IGFBP-5, IBP-5 ; IGFBP-5
Pubmed Id	1850258; 1709938; 7511611; 15489334; 1850257; 9883900; 22117064; 26091039; 9822601
Regulatory	RUO
Source	E.coli
Endotoxin Level	Less than 1.0 EU/μg as determined by LAL method.
Bioactivity	Fully biologically active when compared to standard. The ED50 as determined by its ability to inhibit IGF-II induced proliferation of MCF-7 cells is less than 0.4 μg/ml, corresponding to a specific activity of >2500 IU/mg in the presence of 15 ng/ml of rHuIGF-II.
Expression Region	21-272aa
Mol Weight	28.6 kDa
Nature	recombinant
Protein Description	Full Length of Mature Protein

Subcellular Location	Secreted
Uniprot	P24593, P24593
Database Links	HGNC:5474 OMIM:146734 KEGG:hsa:3488 STRING:9606.ENSP00000233813 UniGene:Hs.607212
Function	IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors.
Research Area	Cancer
Tissue Specificity	Osteosarcoma, and at lower levels in liver, kidney and brain.
Weight	28.6 kDa

Buffer	0.2 µm filtered PBS, pH 7.0,lyophilized
Purity	>96% as determined by SDS-PAGE and HPLC.
Storage Buffer	0.2 μm filtered PBS, pH 7.0 ,lyophilized

Immunogen Species	Homo Sapiens (Human)

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SKU	Supplier No.	Size	Your price	Quantity
BHP10500184	CSB-AP002501HU	500ug	$2618		Add to Cart
BHP10500184	CSB-AP002501HU	100ug	$1166		Add to Cart
BHP10500184	CSB-AP002501HU	5ug	$142		Add to Cart

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