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Home / Proteins & Peptide

Recombinant Human IL6

SKU : BHP10900039

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Applied Biological Materials (abm) Inc.

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Mfr.No.	Z102955
Description	IL6 is a pleiotropic cytokine that participates in a wide variety of biological functions such as acute phase response, inflammation, hematopoiesis, bone metabolism and cancer. While produced mainly by stimulated monocytes, fibroblasts and endothelial cells, IL6 is also known to be produced by macrophages, T cells, B lymphocytes, granulocytes, smooth muscle cells, eosinophils, chondrocytes, osteoblasts, mast cells, glial cells and keratinocytes, upon stimulation. Unlike murine IL6 which is inactive on human cells, both human and murine IL6 are equally active on murine cells. The IL6 receptor is a strongly glycosylated protein of 80 kDa and a length of 449 amino acids (designated CD126). Recombinant human IL6 is expressed in human 293 cells as a monomeric glycoprotein with a molecular mass of 21 to 29 kDa.
Alternative Names	B cell stimulatory factor 2 ; BSF-2 ; CTL differentiation factor ; CDF ; HPGF ; HSF ; MGI-2 ; Hybridoma growth factor ; Interferon beta-2 ; IFN-beta 2 ; IL-6 ; B cell differentiation factor ; BCDF
Quantity	10 µg
Regulatory	RUO
Source	HEK293
Host	Human
Endotoxin Level	<1 EU/µg of recombinant protein as determined by the LAL method
Biological Activity Comment	The EC(50) as determined bythe dose-dependent stimulation of the proliferation of 7TD1 cells (mouse hybridoma cell line) was found to be ≤ 1 ng/mL.

Weight	21 and 29 kDa, monomer, glycosylated

Description	A quick spin of the vial followed by reconstitution in sterile 1xPBS containing 0.1% endotoxin-free recombinant human serum albumin (HSA).
Format	Lyophilized Powder 1x PBS
Purity	>95% as determined by SDS-PAGE
Storage	The lyophilized protein is stable for at least one year from date of receipt at -70°C. Upon reconstitution, this cytokine can be stored in working aliquots at 2° - 8°C for one month, or at -20°C for six months. Avoid repeated freeze/thaw cycles.

Immunogen Species	Homo Sapiens (Human)

MSDS	Growth Factors, Cytokines & Kinases MSDS
Other	Growth Factor and Cytokine Brochure

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SKU	Supplier No.	Size	Your price	Quantity
BHP10900039	Z102955	10µg	$254.44		Add to Cart

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