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Home / Proteins & Peptide

Recombinant Human IL6

SKU : BHP10900023

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Applied Biological Materials (abm) Inc.

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Mfr.No.	Z101315
Description	IL-6 is a pleiotropic cytokine that participates in a wide variety of biological functions such as acute phase response, inflammation, hematopoiesis, bone metabolism and cancer. While produced mainly by stimulated monocytes, fibroblasts and endothelial cells, IL-6 is also known to be produced by macrophages, T cells, B lymphocytes, granulocytes, smooth muscle cells, eosinophils, chondrocytes, osteoblasts, mast cells, glial cells and keratinocytes, upon stimulation. Unlike murine IL-6 which is inactive on human cells, both human and murine IL-6 are equally active on murine cells. The IL-6 receptor is a strongly glycosylated protein of 80 kDa and a length of 449 amino acids (designated CD126). Recombinant human IL-6 is a 21 kDa, glycosylated protein that contains two disulfide bridges.
Alternative Names	IL-6/26 kDa protein ; B cell stimulatory factor 2 ; BSF-2 ; B cell differentiation factor ; BCDF ; CTL differentiation factor ; CDF ; Hybridoma growth factor ; Interferon beta-2 ; IFN-beta-2 ; IFNB2 ; HPGF ; HSF ; MGI-2 ; IL-6
Quantity	25 µg
Regulatory	RUO
Source	CHO cells
Host	Human
Endotoxin Level	<1.0 EU/μg of recombinant protein as determined by the LAL method.
Biological Activity Comment	The ED(50) was determined by the dose-dependent stimulation of the proliferation of murine 7TD1 cells was found to be less than 0.1 ng/mL, corresponding to specific activity of 1.0 x 10^7 IU/mg.

Weight	21.0 kDa

Description	A quick spin of the vial followed by reconstitution in sterile PBS to a concentration not less than 0.1 mg/mL. This solution can then be diluted into other buffers.
Format	Lyophilized Powder Interleukin-6 was lyophilized from a 0.2 μm filtered PBS solution pH 7.0.
Purity	>95% as determined by SDS-PAGE
Storage	The lyophilized protein is stable for at least one year from date of receipt at -70°C. Upon reconstitution, this cytokine can be stored in working aliquots at 2° - 8°C for one month, or at -20°C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles.

Immunogen Species	Homo Sapiens (Human)

MSDS	Growth Factors, Cytokines & Kinases MSDS
Other	Growth Factor and Cytokine Brochure

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SKU	Supplier No.	Size	Your price	Quantity
BHP10900023	Z101315	25µg	$647		Add to Cart

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