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Home / Proteins & Peptide

Recombinant Human IL4RA/CD124 Protein (mFc Tag)

SKU : BHP10304568

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Elabscience Biotechnology Co.,Ltd

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Mfr.No.	PKSH033612
Alternative Names	Interleukin-4 receptor subunit alpha; IL-4 receptor subunit alpha; IL-4R subunit alpha; IL-4R-alpha; IL-4RA; CD124; IL-4-binding protein; IL4-BP; IL4R; IL4RA
Reconstitution	Please refer to the printed manual for detailed information.
Background	Interleukin 4 Receptor alpha (IL4-Ra) is a widely expressed 140 kDa transmembrane glycoprotein in the class I cytokine receptor family. Mature human IL4-Ra consists of a 207 amino acid (aa) extracellular domain (ECD) that contains a cytokine binding region and one fibronectin type III domain; a 24 aa transmembrane segment; and a 569 aa cytoplasmic domain that contains one Box 1 motif and one ITIM motif. IL4-Ra plays an important role in Th2-biased immune responses; alternative macrophage activation; mucosal immunity; allergic inflammation; tumor progression; and atherogenesis. Soluble forms of IL4-Ra; generated by alternate splicing or proteolysis; retain ligand binding properties and inhibit IL-4 bioactivity.
Reactivity	Human
Tag	C-mFc
Description	Recombinant Human Interleukin-4 Receptor Subunit Alpha is produced by our Mammalian expression system and the target gene encoding Met26-Gln231 is expressed with a mFc tag at the C-terminus.
Formulation	Lyophilized from a 0.2 um filtered solution of PBS;pH 7.4.
Host	Human Cells
Accession Number	P24394
Endotoxin Level	< 1.0 EU per ?g as determined by the LAL method.
Mol Weight	50.2 kDa
Mw(kda)	50.2 kDa

Sequence Info	Met26-Gln231

Shipping	This product is provided as lyophilized powder which is shipped with ice packs.
Stotage Note	Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Purity	> 95% as determined by reducing SDS-PAGE.

Product Manual	Data Sheet

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SKU	Supplier No.	Size	Your price	Quantity
BHP10304568	PKSH033612	10ug	$129		Add to Cart
BHP10304568	PKSH033612	50ug	$375		Add to Cart

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