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Home / Proteins & Peptide

Recombinant Human IL36RN (IL1F5)

SKU : BHP10900185

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Applied Biological Materials (abm) Inc.

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Mfr.No.	Z102647
Description	Human IL36RN (IL1F5) is one of the cytokines from the interleukin 1 family encoded by a cluster of genes on chromosome 2. All members of this family show a 12 beta -strand, beta -trefoil configuration. IL36RN is a secreted protein monomer which is also known as interleukin 36 receptor antagonist (IL36RA). This cytokine is predominantly expressed in keratinocytes and a variety of other cell types including brain leukocytes, dendritic cells and macrophage cell types. IL36RN has shown increased expression in lesional psoriasis skin and is thought to play a role in skin inflammation. IL1F5 is a specific antagonist of the IL1 receptor related protein 2 - mediated response to IL1F9. It is also known to specifically inhibit the activation of NF-Kappa-B transcription factor which is induced by IL1F6.
Alternative Names	IL1RP3 ; Interleukin-36 receptor antagonist protein ; IL36RN FIL1D ; IL1F5 ; IL1HY1 ; IL1L1
Quantity	100 µg
Regulatory	RUO
Source	E. coli
Host	Human
Endotoxin Level	<1.0 EU/μg of recombinant protein as determined by the LAL method

Description	A quick spin of the vial followed by reconstitution in sterile distilled water to a concentration not less than 0.1 mg/mL is recommended. This solution can then be diluted into other buffers.
Format	Lyophilized from a 0.2 μm filtered solution in Tris, NaCl and KCl
Purity	>95% as determined by SDS-PAGE
Storage	This protein can be stored in working aliquots at 2° - 8°C for one month, or at -20°C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles.

Immunogen Species	Homo Sapiens (Human)

MSDS	Growth Factors, Cytokines & Kinases MSDS
Other	Growth Factor and Cytokine Brochure

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SKU	Supplier No.	Size	Your price	Quantity
BHP10900185	Z102647	100µg	$299.44		Add to Cart

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