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Home / Proteins & Peptide

Recombinant Human IL36G/IL1F9 Protein (Active)

SKU : BHP10303678

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Elabscience Biotechnology Co.,Ltd

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Mfr.No.	PKSH032644
Alternative Names	Interleukin-36 gamma; IL36G; IL-1-related protein 2; IL-1RP2; IL-1 epsilon; IL-1F9; Interleukin-1 homolog 1; IL-1H1;IL1E;IL1F9;IL1H1;IL1RP2
Reconstitution	Please refer to the printed manual for detailed information.
Background	Interleukin-36 gamma (IL-36gamma) is a member of the interleukin 1 cytokine family that includes three closely related genes, IL-36alpha, beta, and gamma, formerly known as IL-1F6, F8, and F9 respectively. IL-36alpha has been detected in both neuronal and synovial tissue, whereas IL-36beta and IL-36gamma are expressed in both cutaneous and mucosal epithelial cells, including the respiratory tract. IL-36beta and IL-36gamma stimulate proliferation, maturation and/or cytokine expression by innate immune cells (such as keratinocytes and dendritic cells), and adaptive immune cells (neutrophils and T-cells) in both humans and mice. The activity of IL-36alpha is mediated by interleukin 1 receptor-like 2 (IL1RL2/IL1R-rp2), and is specifically inhibited by interleukin 1 family, member 5 (IL1F5/IL-1 delta). IL-36gamma plays an important role in communicating the cell death to surrounding cells.
Reactivity	Human
Description	Recombinant Human Interleukin-36 gamma is produced by our E.coli expression system and the target gene encoding Ser18-Asp169 is expressed.
Formulation	Lyophilized from a 0.2 um filtered solution of 20mM Tris,100mM Nacl,0.1mM EDTA,pH8.0.
Host	E.coli
Accession Number	Q9NZH8
Endotoxin Level	< 1.0 EU per ug as determined by the LAL method.
Bioactivity	Measured by its ability to induce IL-8 secretion in A431 human epithelial carcinoma cells. The ED50 for this effect is 5-20 ng/ml.
Mol Weight	17.0 kDa
Mw(kda)	17.0 kDa

Sequence Info	Ser18-Asp169

Shipping	This product is provided as lyophilized powder which is shipped with ice packs.
Stotage Note	Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Purity	> 95 % as determined by reducing SDS-PAGE.

Product Manual	Data Sheet

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SKU	Supplier No.	Size	Your price	Quantity
BHP10303678	PKSH032644	10ug	$178		Add to Cart
BHP10303678	PKSH032644	50ug	$523		Add to Cart

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