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Home / Proteins & Peptide

Recombinant Human IL29 (IFNL1)

SKU : BHP10901204

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Applied Biological Materials (abm) Inc.

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Mfr.No.	Z102927
Description	The IFN-lambda gene family is composed of three distinct genes: IFN-lambda1 (IL29), IFN-lambda2 (IL28A), and IFN-lambda3 (IL28B). IFN-lambda proteins exhibit only weak homology to IL10, but like IL10, they also use the IL10R2 chain as a component of their receptor complex. The IFN-receptor complex consists of the unique ligand-binding chain IFN- R. The IFN-lambda-1 gene is found exclusively in primate genomes and is 81% identical to IFN-lambda-2/3. IFN-lambda-s, which are now collectively referred to as type III IFNs, exhibit several features in common with type I IFNs, such as antiviral, antiproliferative, and antitumor activities. Recombinant Human IL29 is expressed in human 293 cells as a glycoprotein with a molecular mass of 29 and 35 kDa.
Alternative Names	Interferon lambda-1 ; IFN-lambda-1 ; Cytokine Zcyto21 ; IL-29
Quantity	100 µg
Regulatory	RUO
Source	HEK293
Host	Human
Endotoxin Level	<1 EU/µg of recombinant protein as determined by the LAL method
Biological Activity Comment	The EC(50) as determined by the dose-dependent protection of the cytopathic effect on A549 cells (human lung adenocarcinoma epithelial cell line) that were challenged with encephalomyocarditis (EMC) virus was found to be ≤ 5 ng/mL.

Weight	29 and 35 kDa, monomer, glycosylated

Description	A quick spin of the vial followed by reconstitution in sterile 1xPBS containing 0.1% endotoxin-free recombinant human serum albumin (HSA).
Format	Lyophilized Powder 1x PBS
Purity	>95% as determined by SDS-PAGE
Storage	The lyophilized protein is stable for at least one year from date of receipt at -70°C. Upon reconstitution, this cytokine can be stored in working aliquots at 2° - 8°C for one month, or at -20°C for six months. Avoid repeated freeze/thaw cycles.

Immunogen Species	Homo Sapiens (Human)

MSDS	Growth Factors, Cytokines & Kinases MSDS
Other	Growth Factor and Cytokine Brochure

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SKU	Supplier No.	Size	Your price	Quantity
BHP10901204	Z102927	100µg	$1920.50		Add to Cart

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