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Home / Proteins & Peptide

Recombinant Human IL1RL1/ST2 Protein

SKU : BHP10303077

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Elabscience Biotechnology Co.,Ltd

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Mfr.No.	PKSH031873
Description	The secreted isoform of human IL1RL1 (NP_003847.2) (Met 1-Phe 328) with five amino acids (DDDDK) at the C-terminus was expressed and purified.
Alternative Names	DER4;FIT-1;IL1RL1;IL33R;IL?1 R4;ST2;ST2L;ST2V;T1
Reconstitution	Please refer to the printed manual for detailed information.
Background	IL-1 receptor–like 1 (IL1RL1) is a membrane receptor involved in TH2 inflammatory responses and eosinophilia. It has previously been described that levels of the interlukin-1 like 1 (IL1RL1) protein can be used to diagnose cardiovascular disease and determine the prognosis for a patient with cardiovascular disease. The ligand for IL1RL1 has been described, and named IL-33. Mutants in IL1RL1 have been associated with blood eosinophil counts in a genome-wide association study and with asthma in family-based and case-control studies. As an important mediator involved in many immune and inflammatory responses, this cytokine has been implicated as a regulator of both the development and effector phases of type 2 helper T cell responses, and as a negative feedback modulator of macrophage pro-inflammatory function. IL33 is a specific ligand of ST2L and induces production of Th2 cytokines.
Reactivity	Human
Formulation	Lyophilized from sterile 50mM Tris, 100mM NaCl, pH 8.0
Host	HEK293 Cells
Accession Number	NP_003847.2
Endotoxin Level	< 1.0 EU per ug as determined by the LAL method.
Mol Weight	35.6 kDa
Mw(kda)	35.6 kDa

Sequence Info	Met 1-Phe 328

Shipping	This product is provided as lyophilized powder which is shipped with ice packs.
Stotage Note	Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Purity	> 95 % as determined by reducing SDS-PAGE.

Product Manual	Data Sheet

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SKU	Supplier No.	Size	Your price	Quantity
BHP10303077	PKSH031873	100ug	$732		Add to Cart

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