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Home / Proteins & Peptide

Recombinant Human IL18BP

SKU : BHP10901221

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Applied Biological Materials (abm) Inc.

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Mfr.No.	Z101045
Description	IL-18BP is a secreted protein that binds IL-18 with high affinity and prevents its interaction with the IL-18R. Different isoforms of IL-18BP have been demonstrated, four in human and two in the murine system, and biological activity is limited to particular isoforms. IL-18 binding protein is a constitutively expressed and secreted protein that resembles the extracellular domains of Ig-like receptors but has no transmembrane form. Because IL-18 is one of the early signals leading to IFN-gamma production by Th1 cells, blocking IL-18 activity by IL-18BP may be involved in down-modulation of the early phases of immune responses.
Alternative Names	IL-18BP ; Tadekinig-alfa
Quantity	200 µg
Regulatory	RUO
Source	HEK cells
Host	Human
Endotoxin Level	<1.0 EU/μg of recombinant protein as determined by the LAL method.
Biological Activity Comment	The activity of recombinant Interleukin-18 Binding Protein was determined by the ability to bind IL-18 in functional ELISA.

Weight	19.0 kDa

Description	A quick spin of the vial followed by reconstitution in distilled water to a concentration not less than 0.1 mg/mL. This solution can then be diluted into other buffers.
Format	Lyophilized Powder Recombinant IL-18BP is supplied as an 0.2 μm filtered PBS solution.
Purity	>95% as determined by SDS-PAGE
Storage	The lyophilized protein is stable for at least one year from date of receipt at -70°C. Upon reconstitution, this cytokine can be stored in working aliquots at 2° - 8°C for one month, or at -20°C for six months, with a carrier protein without detectable loss of activity.

Immunogen Species	Homo Sapiens (Human)

MSDS	Growth Factors, Cytokines & Kinases MSDS
Other	Growth Factor and Cytokine Brochure

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SKU	Supplier No.	Size	Your price	Quantity
BHP10901221	Z101045	200µg	$683		Add to Cart

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