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Home / Proteins & Peptide

Recombinant Human IL17F

SKU : BHP10900125

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Applied Biological Materials (abm) Inc.

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Mfr.No.	Z102867
Description	Interleukin 17F is a disulfide-linked homodimeric protein belonging to the IL17 family of proinflammatory cytokines. Members belonging to this family share conserved features of cysteine-knot structures but differ in their N-terminal regions. The T-helper cell produced IL17 family is inducible by IL15 and IL23, and IL17F induces T-cell and PBMC activation and proliferation. It also performs cartilage matrix turnover and angiogenesis prevention. IL17F is the most homologous to IL17 in the IL17 family and dimerizes in a way similar to that of nerve growth factors (NGF) and other neurotrophins. Recombinant Human IL17F expressed in human 293 cells is a homodimeric glycoprotein with a molecular mass of 38 kDa.
Alternative Names	Cytokine ML-1
Quantity	100 µg
Regulatory	RUO
Source	HEK293
Host	Human
Endotoxin Level	<1 EU/µg of recombinant protein as determined by the LAL method
Biological Activity Comment	The EC(50) as determined by the dose-dependent induction of IL-6 secretion from NHDF Adult fibroblasts was found to be ≤ 10 ng/mL.

Weight	38 kDa, homodimer, glycosylated

Description	A quick spin of the vial followed by reconstitution in sterile 1xPBS containing 0.1% endotoxin-free recombinant human serum albumin (HSA).
Format	Lyophilized Powder 1x PBS
Purity	>95% as determined by SDS-PAGE
Storage	The lyophilized protein is stable for at least one year from date of receipt at -70°C. Upon reconstitution, this cytokine can be stored in working aliquots at 2° - 8°C for one month, or at -20°C for six months. Avoid repeated freeze/thaw cycles.

Immunogen Species	Homo Sapiens (Human)

MSDS	Growth Factors, Cytokines & Kinases MSDS
Other	Growth Factor and Cytokine Brochure

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SKU	Supplier No.	Size	Your price	Quantity
BHP10900125	Z102867	100µg	$1160		Add to Cart

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