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Home / Proteins & Peptide

Recombinant Human IL-23 Recetor/IL-23R Protein (Fc Tag)(Active)

SKU : BHP10303624

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Elabscience Biotechnology Co.,Ltd

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Mfr.No.	PKSH032579
Description	Recombinant Human Interleukin-23 Receptor is produced by our Mammalian expression system and the target gene encoding Gly24-Asp353 is expressed with a Fc tag at the C-terminus.
Alternative Names	Interleukin-23 receptor; IL23R; IL-23 receptor; IL-23R
Reconstitution	Please refer to the printed manual for detailed information.
Background	Interleukin 23 receptor (IL23R) is a type I cytokine receptor for IL23. IL23 receptor complex is comprised of two subunits; the IL12Rbeta1 subunit; which is shared with several cytokines; and a subunit that is unique to IL-23. IL23; after binding to IL23R; activates memory T cells and mediates pro-inflammatory activities in part by the production of IL17 through activation of TH17 lymphocytes. IL23R is expressed on T cells; NK cells; dendritic cells; and macrophages. In fact; polymorphisms of the IL23R gene were reported to be associated with susceptibility to inflammatory diseases and autoimmune diseases such as psoriasis; multiple sclerosis; Graves's ophtalmopathy and inflammatory bowel diseases. The IL23R is known to be critically involved in the carcinogenesis of different malignant tumor.
Reactivity	Human
Tag	C-Fc
Formulation	Lyophilized from a 0.2 um filtered solution of PBS; pH7.4.
Host	Human Cells
Accession Number	Q5VWK5
Endotoxin Level	< 1.0 EU per ug as determined by the LAL method.
Bioactivity	Immobilized Human IL-23-His at 0.1ug/ml(100 ul/well) can bind Human IL-23R-Fc. The ED50 of Human IL-23R-Fc is 3.78 ug/ml .
Mol Weight	65.0 kDa
Mw(kda)	65.0 kDa

Sequence Info	Gly24-Asp353

Shipping	This product is provided as lyophilized powder which is shipped with ice packs.
Stotage Note	Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Purity	> 90 % as determined by reducing SDS-PAGE.

Product Manual	Data Sheet

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SKU	Supplier No.	Size	Your price	Quantity
BHP10303624	PKSH032579	10ug	$117		Add to Cart
BHP10303624	PKSH032579	50ug	$297		Add to Cart

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