IBP-7 is a secreted glycoprotein which mediates skeletal myogenesis by binding to IGF and inhibiting its ability to induce skeletal myoblast differentiation while maintaining a constant growth of myoblasts. It has been shown that IBP-7 suppresses growth of cancer cell lines through an IGF independent pathway.
<1.0 EU/μg of recombinant protein as determined by the LAL method.
Biological Activity Comment
Measured by its ability to bind CCL21 in a functional ELISA
Weight
26.7 kDa
Description
Reconstitute at 100 μg/mL in sterile PBS
Format
Lyophilized PowderLyophilized from a 0.2 μm filtered solution in PBS
Purity
>95% as determined by SDS-PAGE
Storage
The lyophilized protein is stable for at least one year from date of receipt at -70°C. Upon reconstitution, this cytokine can be stored in working aliquots at 2° - 8°C for one month, or at -20°C for six months, with a carrier protein without detectable loss of activity.