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Home / Proteins & Peptide

Recombinant Human IGF1R (N-His tag)

SKU : BHP10900986

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Applied Biological Materials (abm) Inc.

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Mfr.No.	Z500175
Description	IGF1R (Insulin-like Growth Factor 1) is a transmembrane tyrosine kinase receptor that is activated by IGF-1 and by the related growth factor IGF-2 . IGF1R mediates the effects of IGF-1 and plays an important role in growth and anabolic effects in adults. The IGF1R is implicated in several cancers, most notably breast cancer where it is highly overexpressed and functions as an anti-apoptotic agent by enhancing cell survival. In many instances, the anti-apoptotic properties of IGF1R overexpression allows cancerous cells to resist the cytotoxic properties of chemotheraputic drugs or radiotherapy .
Alternative Names	IGFIR ; JTK13 ; MGC142170 ; MGC142172 ; CD221
Tag	N-His tag
Quantity	10 µg
Regulatory	RUO
Source	Insect cells
Host	Human
Biological Activity Comment	The specific activity of IGF1R was determined to be 263 nmol /min/mg as per activity assay protocol

Weight	53.0 kDa

Format	Liquid 50mM NaPhosphate, pH7.0, 300mM NaCl, 150mM imidazole, 0.1mM PMSF, 0.2mM DTT, 25% glycerol.
Purity	70% - 90%
Storage	Store product at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.

Immunogen Species	Homo Sapiens (Human)

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SKU	Supplier No.	Size	Your price	Quantity
BHP10900986	Z500175	10µg	$361.11		Add to Cart

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