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Home / Proteins & Peptide

Recombinant Human HLA class I histocompatibility antigen, alpha chain G(HLA-G)

SKU : BHP10504276

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-EP010509HUa2
Description	Involved in the presentation of foreign antigens to the immune syst. Plays a role in maternal tolerance of the fetus by mediating protection from the deleterious effects of natural killer cells, cytotoxic T-lymphocytes, macrophages and mononuclear cells.
Alternative Names	HLA G antigen,MHC class I antigen G, HLA G antigen ; MHC class I antigen G
Tag	N-terminal 6xHis-SUMO-tagged
Regulatory	RUO
Relevance	Involved in the presentation of foreign antigens to the immune syst. Plays a role in maternal tolerance of the fetus by mediating protection from the deleterious effects of natural killer cells, cytotoxic T-lymphocytes, macrophages and mononuclear cells.
Source	E.coli
Notes	Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Expression Region	25-338aa
Mol Weight	51.6kDa
Nature	Recombinant
Protein Description	Full Length of Mature Protein

Subcellular Location	Isoform 1: Cell membrane, Single-pass type I membrane protein, SUBCELLULAR LOCATION: Isoform 2: Cell membrane, Single-pass type I membrane protein, SUBCELLULAR LOCATION: Isoform 3: Cell membrane, Single-pass type I membrane protein, SUBCELLULAR LOCATION: Isoform 4: Cell membrane, Single-pass type I membrane protein, SUBCELLULAR LOCATION: Isoform 5: Secreted, SUBCELLULAR LOCATION: Isoform 6: Secreted, SUBCELLULAR LOCATION: Isoform 7: Secreted
Uniprot	P17693, P17693
Database Links	HGNC:4964 OMIM:142871 KEGG:hsa:3135 STRING:9606.ENSP00000353472 UniGene:Hs.512152
Function	Involved in the presentation of foreign antigens to the immune system. Plays a role in maternal tolerance of the fetus by mediating protection from the deleterious effects of natural killer cells, cytotoxic T-lymphocytes, macrophages and mononuclear cells.
Pathway	Cellular senescence; Antigen processing and presentation; Natural killer cell mediated cytotoxicity; Endocytosis
Protein Families	MHC class I family
Research Area	Immunology
Tissue Specificity	Expressed in trophoblasts. Expressed in fetal eye and thymus (PubMed:2336406). Also expressed in adult eye (PubMed:1570318). Isoform 4: Expressed in fetal first trimester trophoblasts (PubMed:7589701). Isoform 7: Expressed in first trimester, second trime
Weight	51.6 kDa

Stotage Note	Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.
Buffer	Tris-based buffer，50% glycerol
Purity	Greater than 90% as determined by SDS-PAGE.
Storage	The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Storage Buffer	Tris-based buffer,50% glycerol

Immunogen Species	Homo Sapiens (Human)

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SKU	Supplier No.	Size	Your price	Quantity
BHP10504276	CSB-EP010509HUa2	1mg	$1812		Add to Cart
BHP10504276	CSB-EP010509HUa2	100ug	$419		Add to Cart
BHP10504276	CSB-EP010509HUa2	20ug	$224		Add to Cart

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