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Recombinant Human Histone H2B type 1-C/E/F/G/I(H2BC4),partial

SKU : BHP10501711

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-RP016944h
Alternative Names	Histone H2B.1 AHistone H2B.a ,H2B/aHistone H2B.g ,H2B/gHistone H2B.h ,H2B/hHistone H2B.k ,H2B/kHistone H2B.l ,H2B/l, Histone H2B.1 AHistone H2B.a ; H2B/aHistone H2B.g ; H2B/gHistone H2B.h ; H2B/hHistone H2B.k ; H2B/kHistone H2B.l ; H2B/l
Antigen	HIST1H2BC
Tag	N-terminal GST-tagged
Regulatory	RUO
Relevance	Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a tplate. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome rodeling.Has broad antibacterial activity. May contribute to the formation of the functional antimicrobial barrier of the colonic epithelium, and to the bactericidal activity of amniotic fluid.
Source	E.coli
Notes	Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Expression Region	2-125aa
Mol Weight	40.6kDa
Nature	recombinant
Protein Description	Partial

Subcellular Location	Nucleus, Chromosome
Uniprot	P62807, P62807
Database Links	HGNC:4757 OMIM:602798 KEGG:hsa:3017 STRING:9606.ENSP00000366962 UniGene:Hs.182137
Function	Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.; FUNCTION
Protein Families	Histone H2B family
Research Area	Epigenetics and Nuclear Signaling
Weight	41kDa

Stotage Note	Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.
Buffer	Tris-based buffer，50% glycerol
Purity	Greater than 90% as determined by SDS-PAGE.
Storage	The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Storage Buffer	Tris-based buffer,50% glycerol

Immunogen Species	Homo Sapiens (Human)

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SKU	Supplier No.	Size	Your price	Quantity
BHP10501711	CSB-RP016944h	1mg	$1812		Add to Cart
BHP10501711	CSB-RP016944h	100ug	$419		Add to Cart
BHP10501711	CSB-RP016944h	20ug	$224		Add to Cart

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