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Home / Proteins & Peptide

Recombinant Human Histone-binding protein RBBP7(RBBP7)

SKU : BHP10501311

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-EP621959HU
Alternative Names	Histone acetyltransferase type B subunit 2Nucleosome-remodeling factor subunit RBAP46Retinoblastoma-binding protein 7 ,RBBP-7Retinoblastoma-binding protein p46, Histone acetyltransferase type B subunit 2Nucleosome-remodeling factor subunit RBAP46Retinoblastoma-binding protein 7 ; RBBP-7Retinoblastoma-binding protein p46
Antigen	RBBP7
Tag	N-terminal 6xHis-SUMO-tagged
Regulatory	RUO
Relevance	Core histone-binding subunit that may target chromatin rodeling factors, histone acetyltransferases and histone deacetylases to their histone substrates in a manner that is regulated by nucleosomal DNA. Component of several complexes which regulate chromatin metabolism. These include the type B histone acetyltransferase (HAT) complex, which is required for chromatin assbly following DNA replication; the core histone deacetylase (HDAC) complex, which promotes histone deacetylation and consequent transcriptional repression; the nucleosome rodeling and histone deacetylase complex (the NuRD complex), which promotes transcriptional repression by histone deacetylation and nucleosome rodeling; and the PRC2/EED-EZH2 complex, which promotes repression of homeotic genes during development; and the NURF (nucleosome rodeling factor) complex.
Source	E.coli
Notes	Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Expression Region	1-425aa
Mol Weight	63.8kDa
Nature	recombinant
Protein Description	Full Length

Subcellular Location	Nucleus
Uniprot	Q16576, Q16576
Database Links	HGNC:9890 OMIM:300825 KEGG:hsa:5931 STRING:9606.ENSP00000369424 UniGene:Hs.495755
Function	Core histone-binding subunit that may target chromatin remodeling factors, histone acetyltransferases and histone deacetylases to their histone substrates in a manner that is regulated by nucleosomal DNA. Component of several complexes which regulate chromatin metabolism. These include the type B histone acetyltransferase (HAT) complex, which is required for chromatin assembly following DNA replication; the core histone deacetylase (HDAC) complex, which promotes histone deacetylation and consequent transcriptional repression; the nucleosome remodeling and histone deacetylase complex (the NuRD complex), which promotes transcriptional repression by histone deacetylation and nucleosome remodeling; and the PRC2/EED-EZH2 complex, which promotes repression of homeotic genes during development; and the NURF (nucleosome remodeling factor) complex.
Protein Families	WD repeat RBAP46/RBAP48/MSI1 family
Research Area	Transcription
Weight	63.8kDa

Stotage Note	Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.
Buffer	Tris-based buffer，50% glycerol
Purity	Greater than 90% as determined by SDS-PAGE.
Storage	The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Storage Buffer	Tris-based buffer,50% glycerol

Immunogen Species	Homo Sapiens (Human)

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SKU	Supplier No.	Size	Your price	Quantity
BHP10501311	CSB-EP621959HU	1mg	$1812		Add to Cart
BHP10501311	CSB-EP621959HU	100ug	$419		Add to Cart
BHP10501311	CSB-EP621959HU	20ug	$224		Add to Cart

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