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Home / Proteins & Peptide

Recombinant Human GRO gamma (CXCL3)

SKU : BHP10900720

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Applied Biological Materials (abm) Inc.

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Mfr.No.	Z101469
Description	Growth regulated oncogene-gamma belongs to the family of chemotyctic cytokines called chemokines. It is identical with MGSA (melanoma growth stimulatory activity) and the new designation is CXCL3. This factor is known mainly because of its chemotactic activity. GRO expression is inducible by serum or PDGF and/or by a variety of inflammatory mediators, such as IL-1 and TNF, in monocytes, fibroblasts, melanocytes and epithelial cells. In certain tumor cell lines, GRO is expressed constitutively. Similar to other alpha chemokines, the three GRO proteins are potent neutrophil attractants and activators. In addition, these chemokines are also active toward basophils. All three GROs can bind with high affinity to the IL-8 receptor type B.
Alternative Names	Macrophage inflammatory protein 2-beta ; MIP2-beta ; C-X-C motif chemokine 3 ; GRO-gamma(1-73) ; Growth-regulated protein gamma ; GRO-gamma
Quantity	1.0 mg
Regulatory	RUO
Source	E. coli
Host	Human
Endotoxin Level	<1.0 EU/μg of recombinant protein as determined by the LAL method.
Biological Activity Comment	Determined by its ability to chemoattract 293 transfected CXCR2 cells using a concentration range of 10-100 ng/mL.

Weight	8.0 kDa

Description	A quick spin of the vial followed by reconstitution in distilled water to a concentration not less than 0.1 mg/mL. This solution can then be diluted into other buffers.
Format	Lyophilized Powder Recombinant GRO-gamma/CXCL3 was lyophilized from a 0.2 μm filtered concentrated (1.0 mg/mL) solution in 40 mM NaCl, 10 mM PB, pH 7.0.
Purity	>95% as determined by SDS-PAGE
Storage	The lyophilized protein is stable for at least one year from date of receipt at -70°C. Upon reconstitution, this cytokine can be stored in working aliquots at 2° - 8°C for one month, or at -20°C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles.

Immunogen Species	Homo Sapiens (Human)

MSDS	Growth Factors, Cytokines & Kinases MSDS
Other	Growth Factor and Cytokine Brochure

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SKU	Supplier No.	Size	Your price	Quantity
BHP10900720	Z101469	1.0mg	$836		Add to Cart

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