A DNA sequence encoding the human GMFB (Met1-His142) was expressed.
Alternative Names
Glia maturation factor beta;GMF-beta; GMF
Reconstitution
Please refer to the printed manual for detailed information.
Background
GMFB is a nerve growth factor which belongs to the actin-binding proteins ADF family, GMF subfamily. GMFB is involved in nervous system development, angiogenesis and immune function. It is especially crucial for the nervous system. GMFB causes brain cell differentiation, stimulates neural regeneration and inhibits tumor cell proliferation. It contains 1 ADF-H domain and is phosphorylated after phorbol ester stimulation. GMFB overexpression in astrocytes results in the increase of BDNF production. GMFB expression is increased by exercise, thus BDNF is important for exercise-induction of BDNF.
Reactivity
Human
Formulation
Lyophilized from sterile PBS, pH 7.4
Host
E.coli
Accession Number
NP_004115.1
Endotoxin Level
Please contact us for more information.
Mol Weight
16.7 kDa
Mw(kda)
16.7 kDa
Sequence Info
Met 1-His142
Shipping
This product is provided as lyophilized powder which is shipped with ice packs.
Stotage Note
Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.