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Home / Proteins & Peptide

Recombinant Human GM2A Protein (Human Cells, His Tag)

SKU : BHP10304276

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Elabscience Biotechnology Co.,Ltd

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Mfr.No.	PKSH033306
Description	Recombinant Human Ganglioside GM2 activator is produced by our Mammalian expression system and the target gene encoding Ser32-Ile193 is expressed with a 6His tag at the C-terminus.
Alternative Names	Ganglioside GM2 activator;Cerebroside sulfate activator protein;GM2-AP;Sphingolipid activator protein 3;SAP-3
Reconstitution	Please refer to the printed manual for detailed information.
Background	Ganglioside GM2 activator (GM2A) is a small glycolipid transport protein which acts as a substrate specific co-factor for the lysosomal enzyme beta-hexosaminidase A (HEXB). HEXB together with GM2A, catalyzes the degradation of the ganglioside GM2, and other molecules containing terminal N-acetyl hexosamines. GM2A accommodate several single chain phospholipids and fatty acids, is a lipid transfer protein that stimulates the enzymatic processing of gangliosides, and also T-cell activation through lipid presentation. It extracts single GM2 molecules from membranes and presents them in soluble form to beta-hexosaminidase A for cleavage of N-acetyl-D-galactosamine and conversion to GM3.
Reactivity	Human
Tag	C-6His
Formulation	Lyophilized from a 0.2 um filtered solution of 20mM TrisHCl,150mM NaCl,pH7.5.
Host	Human Cells
Accession Number	P17900
Endotoxin Level	< 1.0 EU per ug as determined by the LAL method.
Mol Weight	18.6 kDa
Mw(kda)	18.6 kDa

Sequence Info	Ser32-Ile193

Shipping	This product is provided as lyophilized powder which is shipped with ice packs.
Stotage Note	Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Purity	> 95 % as determined by reducing SDS-PAGE.

Product Manual	Data Sheet

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SKU	Supplier No.	Size	Your price	Quantity
BHP10304276	PKSH033306	10ug	$178		Add to Cart
BHP10304276	PKSH033306	50ug	$523		Add to Cart

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