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Home / Proteins & Peptide

Recombinant Human GM-CSF (CSF2)

SKU : BHP10900145

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Applied Biological Materials (abm) Inc.

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Mfr.No.	Z101165
Description	GM-CSF is a hematopoietic growth factor that is produced by endothelial cells, monocytes, fibroblasts and T-lymphocytes following their activation by antigens or mitogens. GM-CSF stimulates the development of macrophages and neutrophils and plays a role in the proliferation and development of early erythroid megakaryocytic and eosinophilic progenitor cells. Approximately 90% of the secreted colony stimulating activities are due to GM-CSF. While non-glycosylated and glycosylated GM-CSF show similar activities in vitro, fully glycosylated GM-CSF is biologically more active in vivo compared to its non-glycosylated counterpart. Human and murine GM-CSF are species-specific and therefore, exhibit no cross-reactivity. Recombinant Human GM-CSF is a glycosylated, monomeric protein (contains intra-chain disulfide bonds) that migrates at approximately 25 kDa in a reducing SDS-PAGE.
Alternative Names	CSF ; Molgramostin ; Sargramostim ; pluripoietin-alpha ; GMCSF ; GMCSF ; Colony-stimulating factor
Quantity	50 µg
Regulatory	RUO
Source	CHO cells
Host	Human
Endotoxin Level	<1.0 EU/μg of recombinant protein as determined by the LAL method
Biological Activity Comment	The ED50 as determined by the dose-dependent stimulation of the proliferation of human TF-1 cells was found be to ≤ 0.1 ng/mL

Weight	15.0 kDa

Description	A quick spin of the vial followed by reconstitution in distilled water to a concentration not less than 0.1 mg/mL. This solution can then be diluted into other buffers.
Format	Lyophilized Powder Lyophilized from a 0.2 μm filtered solution in PBS, pH 7.0
Purity	>95% as determined by SDS-PAGE
Storage	The lyophilized protein is stable for at least one year from date of receipt at -70°C. Upon reconstitution, this cytokine can be stored in working aliquots at 2° - 8°C for one month, or at -20°C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles.

Immunogen Species	Homo Sapiens (Human)

MSDS	Growth Factors, Cytokines & Kinases MSDS
Other	Growth Factor and Cytokine Brochure

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SKU	Supplier No.	Size	Your price	Quantity
BHP10900145	Z101165	50µg	$845		Add to Cart

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