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Home / Proteins & Peptide

Recombinant Human GLK (N-GST tag)

SKU : BHP10900010

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Applied Biological Materials (abm) Inc.

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Mfr.No.	Z500153
Description	GLK is a member of the STE20 family of serine/threonine protein kinases and contains N-terminal catalytic domain and C-terminal regulatory domain. GLK is upstream of the MEKK1 target and is stimulated by UV radiation and TNF-? and can lead to the activation of the JNK signaling pathway. GLK can directly activate PKC-? during TCR signaling and people with systemic lupus erythematosus show considerable enhanced GLK expression and activation of PKC-? and the kinase IKK in T cells . GLK can act as a pro-apoptotic kinase which orchestrates activation of BAX via the concerted posttranscriptional modulation of PUMA, BAD, and BIM .
Alternative Names	MAP4K3 ; MAPKKKK3 ; MEKKK3 ; RAB8IPL1
Tag	N-GST tag
Quantity	10 µg
Regulatory	RUO
Source	Insect cells
Host	Human
Biological Activity Comment	The specific activity of GLKwas determined to be 92nmol/min/mg as per activity assay protocol.

Weight	70.0 kDa

Format	Liquid 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.
Purity	70% - 90%
Storage	Store product at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.

Immunogen Species	Homo Sapiens (Human)

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SKU	Supplier No.	Size	Your price	Quantity
BHP10900010	Z500153	10µg	$694.44		Add to Cart

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