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Home / Proteins & Peptide

Recombinant Human GAD67/GAD1 Protein (His Tag)

SKU : BHP10302817

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Elabscience Biotechnology Co.,Ltd

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Mfr.No.	PKSH030814
Description	A DNA sequence encoding the human GAD1 (Q99259-1) (Met 1-Leu 594) was fused with a polyhistidine tag at the C-terminus.
Alternative Names	CPSQ1;GAD;SCP
Reconstitution	Please refer to the printed manual for detailed information.
Background	Glutamate decarboxylase 1, also known as 67 kDa glutamic acid decarboxylase, Glutamate decarboxylase 67 kDa isoform and GAD1, is a member of the group II decarboxylase family. GAD1 is expressed in benign and malignant prostatic tissue and may serve as a highly prostate-specific tissue biomarker. GAD1 isoform 3 is expressed in pancreatic islets, testis, adrenal cortex, and perhaps other endocrine tissues, but not in brain. Tissue-specific markers are useful for identification of tumour type in advanced cancers of unknown origin. In plants, as in most eukaryotes, glutamate decarboxylase catalyses the synthesis of GABA. Root-specific calcium/calmodulin-regulated GAD1 plays a major role in GABA synthesis in plants under normal growth conditions and in response to stress. Defects in GAD1 are the cause of cerebral palsy spastic quadriplegic type 1 (CPSQ1)which is a non-progressive disorder of movement and/or posture resulting from defects in the developing central nervous system. Affected individuals manifest symmetrical, non-progressive spasticity and no adverse perinatal history or obvious underlying alternative diagnosis.
Reactivity	Human
Tag	C-His
Formulation	Lyophilized from sterile 20mM Tris, 500mM NaCl, 10% gly, pH 8.5
Host	Baculovirus-Insect Cells
Accession Number	Q99259-1
Endotoxin Level	< 1.0 EU per ug as determined by the LAL method.
Mol Weight	68.3 kDa
Mw(kda)	68.3 kDa

Sequence Info	Met 1-Leu 594

Shipping	This product is provided as lyophilized powder which is shipped with ice packs.
Stotage Note	Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Purity	> 92 % as determined by reducing SDS-PAGE.

Product Manual	Data Sheet

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SKU	Supplier No.	Size	Your price	Quantity
BHP10302817	PKSH030814	50ug	$732		Add to Cart

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