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Home / Proteins & Peptide

Recombinant Human FLT3 Ligand (FLT3LG)

SKU : BHP10901081

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Applied Biological Materials (abm) Inc.

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Mfr.No.	Z101145
Description	Known to bind to cells that express the tyrosine kinase receptor, FLT3LG promotes long-term expansion and differentiation of human pro-B cells. Human FLT3LG also stimulates the proliferation of cells expressing murine FLT-3 receptors. In combination with SCF and IL3, FLT3LG can cause expansion of cells with the marker spectrum CD34(+)/CD38(-). Alone, FLT3LG supports the survival of precursors in the lineage of blood-forming cells such as CFU-GM, CFU-GEMM, and the very primitive high proliferative potential colony-forming cells, HPP-CFC. FLT3LG has only marginal effects on progenitors for erythroid cells and megakaryocytes. Recombinant Human FLT3LG is a glycosylated, monomeric protein (with intra-chain disulfide bonds) that runs at approximately 26 kDa on a reducing SDS-PAGE.
Alternative Names	FLT-3 ligand ; FLT3L
Quantity	50 µg
Regulatory	RUO
Source	CHO cells
Host	Human
Endotoxin Level	<1.0 EU/μg of recombinant protein as determined by the LAL method
Biological Activity Comment	The ED(50) as determined by the dose-dependent stimulation of the proliferation of Human AML5 cells was found to be in the range of 1.0 ng/mL.

Weight	17.0 kDa

Description	A quick spin of the vial followed by reconstitution in distilled water to a concentration not less than 0.1 mg/mL. This solution can then be diluted into other buffers.
Format	Lyophilized Powder Lyophilized from a 0.2 μm filtered PBS solution pH 7.0
Purity	>95% as determined by SDS-PAGE
Storage	The lyophilized protein is stable for at least one year from date of receipt at -70°C. Upon reconstitution, this cytokine can be stored in working aliquots at 2° - 8°C for one month, or at -20°C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles.

Immunogen Species	Homo Sapiens (Human)

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SKU	Supplier No.	Size	Your price	Quantity
BHP10901081	Z101145	50µg	$1061		Add to Cart

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