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Home / Proteins & Peptide

Recombinant Human FLRT2 Protein (His Tag)(Active)

SKU : BHP10300625

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Elabscience Biotechnology Co.,Ltd

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Mfr.No.	PKSH031164
Description	A DNA sequence encoding the human FLRT2 (O43155) extracellular domain (Met 1-Ser 539) was expressed, with a C-terminal polyhistidine tag.
Alternative Names	UNQ232/PRO265 ; KIAA0405
Background	Fibronectin Leucine-Rich Transmembrane (FLRT) proteins are glycosylated membrane proteins expressed at the cell surface which localise in a homophilic manner to cell-cell contacts expressing the focal adhesion marker vinculin. FLRT1, FLRT2, and FLRT3, the three genes encode putative type I transmembrane proteins, each containing 10 leucine-rich repeats (LRR), a type III fibronectin (FN) domain, followed by the transmembrane region, and a short cytoplasmic tail. FLRT family members may function in cell adhesion and/or receptor signalling. Each member of the FLRT family has a distinct, highly regulated expression patte, as was seen for the NLRR family. FLRT2 is expressed in a subset of the sclerotome, adjacent to the region that forms the syndetome, suggesting that interaction with FGF signalling may be a general property of FLRT proteins. All FLRTs can interact with FGFR1 and FLRTs can be induced by the activation of FGF signalling by FGF-2. FLRT proteins have a dual role, promoting FGF signalling and modulating homotypic cell adhesion. FLRT2 played critical roles in craniofacial development, and it was also present in the vomero-nasal organ, mandibular primodia, and the posterior aspects of the unfused and fused secondary palatal shelves.
Tag	His tag
Regulatory	RUO
Host	Human Cells
Endotoxin Level	< 1.0 EU per μg of the protein as determined by the LAL method
Nature	Recombinant

Shipping	In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
Buffer	Lyophilized from sterile PBS, pH 7.4
Description	Please refer to the printed manual for detailed information.
Purity	> 98 % as determined by SDS-PAGE
Expiry Date	Samples are stable for up to twelve months from date of receipt at -70℃

Immunogen Species	Homo Sapiens (Human)

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SKU	Supplier No.	Size	Your price	Quantity
BHP10300625	PKSH031164	100ug	$732		Add to Cart

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