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Home / Proteins & Peptide

Recombinant Human Fibroblast growth factor 21 protein(FGF21) (Active)

SKU : BHP10500181

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-AP002471HU
Alternative Names	FGF-21
Antigen	FGF21
Pubmed Id	10858549; 12975309; 15489334; 15340161; 15902306; 17623664; 18829467; 19117008; 20094046
Regulatory	RUO
Source	E.coli
Endotoxin Level	Less than 1.0 EU/μg as determined by LAL method.
Bioactivity	Fully biologically active when compared to standard. The ED50 as determined by thymidine uptake assay using FGF-receptors transfected BaF3 cells is less than 0.5 μg/ml, corresponding to a specific activity of >2.0x10³ IU/mg in the presence of 5 ug/ml of rMuKlotho-β and 10 μg/ml of heparin.
Expression Region	29-209aa
Mol Weight	19.4 kDa
Nature	recombinant
Protein Description	Full Length of Mature Protein

Subcellular Location	Secreted
Uniprot	Q9NSA1, Q9NSA1
Database Links	HGNC:3678 OMIM:609436 KEGG:hsa:26291 STRING:9606.ENSP00000222157 UniGene:Hs.283015
Function	Stimulates glucose uptake in differentiated adipocytes via the induction of glucose transporter SLC2A1/GLUT1 expression (but not SLC2A4/GLUT4 expression). Activity requires the presence of KLB.
Pathway	MAPK signaling pathway; PI3K-Akt signaling pathway; Regulation of actin cytoskeleton; Ras signaling pathway; Rap1 signaling pathway
Protein Families	Heparin-binding growth factors family
Research Area	Cancer
Weight	19.4 kDa

Buffer	0.2 µm filtered PBS, pH 7.4,lyophilized
Purity	>96% as determined by SDS-PAGE and HPLC.
Storage Buffer	0.2 μm filtered PBS, pH 7.4 ,lyophilized

Immunogen Species	Homo Sapiens (Human)

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SKU	Supplier No.	Size	Your price	Quantity
BHP10500181	CSB-AP002471HU	500ug	$2618		Add to Cart
BHP10500181	CSB-AP002471HU	100ug	$1166		Add to Cart
BHP10500181	CSB-AP002471HU	5ug	$142		Add to Cart

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