FGF-20 is a heparin binding protein of the FGF family which works to control cell division, differentiation, and function. These proteins are especially prominent during prenatal development and postnatal growth. FGF-20 shares a high degree of homology with FGF-9 and FGF-16. The group of receptors which FGF-20 binds to comprises of FGFR1c, FGFR2c, FGFR3b, FGFR3c and FGFR4. It is shown that FGF-20 is found in a variety of cells, including but limited to, dopaminergic neurons, fibroblasts, keratinocytes and breast epithelium.
Alternative Names
FGF-20
Quantity
30 µg
Regulatory
RUO
Source
E. coli
Host
Human
Endotoxin Level
<1.0 EU/μg of recombinant protein as determined by the LAL method.
Biological Activity Comment
Measured in a cell proliferation assay using NR6R-3T3 mouse fibroblast cells
Weight
23.5 kDa
Description
Reconstitute at 10 μg/mL in sterile PBS containing at least 0.1% human or bovine serum albumin
Format
Lyophilized PowderLyophilized from a 0.2 μm filtered solution in 10mM MOPS, 10mM ammonium sulphate, 0.2mM DTT and 0.2mM EDTA (pH 7.0).
Purity
>95% as determined by SDS-PAGE
Storage
The lyophilized protein is stable for at least one year from date of receipt at -70°C. Upon reconstitution, this cytokine can be stored in working aliquots at 2° - 8°C for one month, or at -20°C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles.