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Home / Proteins & Peptide

Recombinant Human FAK (N-GST tag)

SKU : BHP10901058

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Applied Biological Materials (abm) Inc.

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Mfr.No.	Z500137
Description	FAK (Focal Adhesion Kinase) is a non-receptor protein tyrosine kinase involved in signal transduction from integrin-enriched focal adhesion sites that mediate cell contact with the extracellular matrix. FAK-enhanced signals have been shown to mediate the survival of anchorage-dependent cells and are critical for efficient cell migration in response to growth factor receptor and integrin stimulation . Elevated expression of FAK in human tumors has been correlated with increased malignancy and invasiveness . Elevated FAK expression in anaplastic astrocytoma and glioblastoma tumor biopsy samples has been demonstrated.
Alternative Names	FADK ; FAK1 ; FRNK ; pp125FAK ; PTK2
Tag	N-GST tag
Quantity	10 µg
Regulatory	RUO
Source	Insect cells
Host	Human
Biological Activity Comment	The specific activity of FAK was determined to be 28 nmol /min/mg as per activity assay protocol.

Weight	140.0 kDa

Format	Liquid 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.
Purity	70% - 90%
Storage	Store product at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.

Immunogen Species	Homo Sapiens (Human)

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SKU	Supplier No.	Size	Your price	Quantity
BHP10901058	Z500137	10µg	$361.11		Add to Cart

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