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Home / Proteins & Peptide

Recombinant Human ERK1 (N-GST tag)

SKU : BHP10900262

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Applied Biological Materials (abm) Inc.

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Mfr.No.	Z500131
Description	ERK1 is a protein serine/threonine kinase that is a member of the extracellular signal-regulated kinases (ERKs), also known as mitogen-activated protein kinase 3 (MAPK3) which are activated in response to numerous growth factors and cytokines. ERK1 is ubiquitously distributed in tissues with the highest expression in heart, brain and spinal cord. Activated ERK1 translocates into the nucleus where it phosphorylates various transcription factors (e.g., Elk-1, c-Myc, c-Jun, c-Fos, and C/EBP beta). ERK pathway is necessary for experience-dependent plasticity and for long-term potentiation of synaptic transmission in the developing visual cortex . ERK activation affects the axonal growth by phosphorylation of microtubule-associated proteins and neurofilaments .
Alternative Names	P44ERK1 ; P44MAPK ; HS44KDAP ; HUMKER1A ; MGC20180 ; MAPK3 ; PRKM3
Tag	N-GST tag
Quantity	10 µg
Regulatory	RUO
Source	Insect cells
Host	Human
Biological Activity Comment	The specific activity of ERK1 was determined to be 840 nmol /min/mg as per activity assay protocol.

Weight	72.0 kDa

Format	Liquid 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.
Purity	70% - 90%
Storage	Store product at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.

Immunogen Species	Homo Sapiens (Human)

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SKU	Supplier No.	Size	Your price	Quantity
BHP10900262	Z500131	10µg	$361.11		Add to Cart

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