Both Eotaxin-2/CCL24 and Eotaxin-3/CCL26 are CC chemokines and functional ligands for CC chemokine receptor 3 (CCR3), which is preferentially expressed on eosinophils. Only 34% of the amino acids in Eotaxin-2/CCL24 and Eotaxin-3/CCL26 are identical, but these two chemokines have a common characteristic feature in terms of chemotaxis for eosinophils via the CCR3.
<1.0 EU/μg of recombinant protein as determined by the LAL method.
Biological Activity Comment
Not available.
Weight
9.0 kDa
Description
A quick spin of the vial followed by reconstitution in distilled water to a concentration not less than 0.1 mg/mL. This solution can then be diluted into other buffers.
Format
Lyophilized PowderRecombinant Eotaxin-3 is presented as 0.2 μm filtered PBS pH 7.5 with 10% glycerol.
Purity
>95% as determined by SDS-PAGE
Storage
Upon reconstitution, this cytokine can be stored in working aliquots at 2° - 8°C for one month, or at -20°C for six months.