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Home / Proteins & Peptide

Recombinant Human Endoglin/CD105 Protein (His&Trx Tag)

SKU : BHP10303443

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Elabscience Biotechnology Co.,Ltd

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Mfr.No.	PKSH032379
Description	Recombinant Human Endoglin is produced by our E.coli expression system and the target gene encoding Glu26-Gln176 is expressed with a Trx, 6His tag at the N-terminus.
Alternative Names	Endoglin; END; CD105; ENG;HHT1;ORW1
Reconstitution	Please refer to the printed manual for detailed information.
Background	Endoglin is a single-pass type I membrane protein which restricted to endothelial cells in all tissues except bone marrow. Endoglin as major glycoprotein of vascular endothelium, it has been found on endothelial cells, activated macrophages, fibroblasts, and smooth muscle cells. Furthermore, Homodimer forms a heteromeric complex with the signaling receptors for transforming growth factor-beta: TGFBR1 and/or TGFBR2. It may have an important role in the binding of endothelial cells to integrins and/or other RGD receptors. Defects in ENG are the cause of hereditary hemorrhagic telangiectasia type 1 (HHT1), which is an autosomal dominant multisystemic vascular dysplasia, characterized by recurrent epistaxis, muco-cutaneous telangiectases, gastro-intestinal hemorrhage, and pulmonary (PAVM), cerebral (CAVM) and hepatic arteriovenous malformations.
Reactivity	Human
Tag	N-Trx
Formulation	Supplied as a 0.2 um filtered solution of 20mM PB?150mM NaCl,pH7.4.
Host	E.coli
Accession Number	P17813-1
Endotoxin Level	< 1.0 EU per ug as determined by the LAL method.
Mol Weight	33.6 kDa
Mw(kda)	33.6 kDa

Sequence Info	Glu26-Gln176

Shipping	This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs.Upon receipt, store it immediately at<-20°C.
Stotage Note	Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Purity	> 95 % as determined by reducing SDS-PAGE.

Product Manual	Data Sheet

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SKU	Supplier No.	Size	Your price	Quantity
BHP10303443	PKSH032379	10ug	$275		Add to Cart
BHP10303443	PKSH032379	50ug	$525		Add to Cart

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