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Home / Proteins & Peptide

Recombinant Human EIF2AK3 (N-GST tag)

SKU : BHP10900465

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Applied Biological Materials (abm) Inc.

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Mfr.No.	Z500117
Description	EIF2AK3 phosphorylates the alpha subunit of eukaryotic translation-initiation factor 2 (EIF2) leading to its inactivation and a rapid reduction of translational initiation and repression of global protein synthesis. EIF2AK3 is a type I membrane protein located in the endoplasmic reticulum (ER), where it is induced by ER stress caused by malfolded proteins . EIF2AK3 plays a major role in the ability of cells to adapt to ER stress and is also involved in an integrated adaptive response to hypoxic stress in HeLa cells . EIF2AK3 functions in iron homeostasis and may play a role in hemolytic and inflammatory anemia.
Alternative Names	PEK ; WRS ; HRI ; DKFZp781H1925 ; PERK
Tag	N-GST tag
Quantity	10 µg
Regulatory	RUO
Source	Insect cells
Host	Human
Biological Activity Comment	The specific activity of EIF2K3 was determined to be 18 nmol /min/mg as per activity assay protocol.

Weight	115.0 kDa

Format	Liquid 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.
Purity	70% - 90%
Storage	Store product at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.

Immunogen Species	Homo Sapiens (Human)

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SKU	Supplier No.	Size	Your price	Quantity
BHP10900465	Z500117	10µg	$361.11		Add to Cart

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