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Home / Proteins & Peptide

Recombinant Human EIF2AK1 (HRI) (N-GST tag)

SKU : BHP10900201

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Applied Biological Materials (abm) Inc.

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Mfr.No.	Z500115
Description	EIF2AK1 (HRI) or eukaryotic translation initiation factor 2-alpha kinase 1 acts at the level of translation initiation to downregulate protein synthesis in response to stress. EIF2AK1 (HRI) is a kinase that can be inactivated by hemin and is activated by heme deficiency and other stimuli and is a major protein kinase that phosphorylates EIF2-alpha . EIF2AK1 (HRI) is downregulated in the majority of ovarian cancers compared with normal ovarian tissues. EIF2AK1 (HRI) functions in iron homeostasis and may play a role in hemolytic and inflammatory anemia .
Alternative Names	HRI ; KIAA1369 ; HCR
Tag	N-GST tag
Quantity	10 µg
Regulatory	RUO
Source	Insect cells
Host	Human
Biological Activity Comment	The specific activity of EIF2AK1 (HRI) was determined to be 12 nmol /min/mg as per activity assay protocol.

Weight	120.0 kDa

Format	Liquid 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.
Purity	70% - 90%
Storage	Store product at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.

Immunogen Species	Homo Sapiens (Human)

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SKU	Supplier No.	Size	Your price	Quantity
BHP10900201	Z500115	10µg	$361.11		Add to Cart

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