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Home / Proteins & Peptide

Recombinant Human E3 ubiquitin-protein ligase pellino homolog 3(PELI3)

BHP10506173
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Contact us to order
Tel
+1 866.986.9598
Email
[email protected]
Get a Quote
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Uniprot Q8N2H9
Database Links

HGNC:30010

OMIM:609827

KEGG:hsa:246330

STRING:9606.ENSP00000322532

UniGene:Hs.656875
Function E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. Involved in the TLR and IL-1 signaling pathways via interaction with the complex containing IRAK kinases and TRAF6. Mediates 'Lys-63'-linked polyubiquitination of IRAK1. Can activate AP1/JUN and ELK1. Not required for NF-kappa-B activation.
Protein Families Pellino family
Research Area Immunology
Tissue Specificity Highly expressed in brain, heart and testis, and at lower level in kidney, liver, lung, placenta, small intestine, spleen and stomach. Isoform 1 is not expressed in lung.
Purity Greater than 85% as determined by SDS-PAGE.
Storage The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20℃/-80℃. The shelf life of lyophilized form is 12 months at -20℃/-80℃.
Storage Buffer Tris-based buffer，50% glycerol
Immunogen Species Homo Sapiens (Human)
SKU Supplier No. Size Your price Quantity
BHP10506173 CSB-EP847618HU 1mg $2466
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BHP10506173 CSB-EP847618HU 100ug $578
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BHP10506173 CSB-EP847618HU 20ug $306
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