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Home / Proteins & Peptide

Recombinant Human Dr1-associated corepressor(DRAP1),partial

SKU : BHP10501810

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-RP051444h
Alternative Names	Dr1-associated protein 1Negative cofactor 2-alpha ,NC2-alpha, Dr1-associated protein 1Negative cofactor 2-alpha ; NC2-alpha
Antigen	DRAP1
Tag	N-terminal GST-tagged
Regulatory	RUO
Relevance	The association of the DR1/DRAP1 heterodimer with TBP results in a functional repression of both activated and basal transcription of class II genes. This interaction precludes the formation of a transcription-competent complex by inhibiting the association of TFIIA and/or TFIIB with TBP. Can bind to DNA on its own.
Source	E.coli
Notes	Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Expression Region	4-198aa
Mol Weight	48.2kDa
Nature	recombinant
Protein Description	Partial

Subcellular Location	Nucleus
Uniprot	Q14919, Q14919
Database Links	HGNC:3019 OMIM:602289 KEGG:hsa:10589 STRING:9606.ENSP00000307850 UniGene:Hs.356742
Function	The association of the DR1/DRAP1 heterodimer with TBP results in a functional repression of both activated and basal transcription of class II genes. This interaction precludes the formation of a transcription-competent complex by inhibiting the association of TFIIA and/or TFIIB with TBP. Can bind to DNA on its own.
Protein Families	NC2 alpha/DRAP1 family
Research Area	Transcription
Tissue Specificity	Ubiquitous. Highly expressed in adult testis, heart, skeletal muscle, pancreas and brain, and in fetal brain, liver and kidney.
Weight	48.6kDa

Stotage Note	Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.
Buffer	Tris-based buffer，50% glycerol
Purity	Greater than 90% as determined by SDS-PAGE.
Storage	The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Storage Buffer	Tris-based buffer,50% glycerol

Immunogen Species	Homo Sapiens (Human)

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SKU	Supplier No.	Size	Your price	Quantity
BHP10501810	CSB-RP051444h	1mg	$1812		Add to Cart
BHP10501810	CSB-RP051444h	100ug	$419		Add to Cart
BHP10501810	CSB-RP051444h	20ug	$224		Add to Cart

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