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Home / Proteins & Peptide

Recombinant Human Docking protein 5(DOK5),partial

SKU : BHP10500488

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-EP007111HU
Alternative Names	Downstream of tyrosine kinase 5Insulin receptor substrate 6 ,IRS-6 ,IRS6, Downstream of tyrosine kinase 5Insulin receptor substrate 6 ; IRS-6 ; IRS6
Antigen	DOK5
Tag	N-terminal 6xHis-SUMO-tagged
Regulatory	RUO
Relevance	DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assbly of multimolecular signaling complexes. DOK5 functions in RET-mediated neurite outgrowth and plays a positive role in activation of the MAP kinase pathway. Putative link with downstream effectors of RET in neuronal differentiation.
Source	E.coli
Notes	Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Expression Region	1-198aa
Mol Weight	38.8kDa
Nature	recombinant
Protein Description	Partial

Uniprot	Q9P104, Q9P104
Database Links	HGNC:16173 OMIM:608334 KEGG:hsa:55816 STRING:9606.ENSP00000262593 UniGene:Hs.473133
Function	DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK5 functions in RET-mediated neurite outgrowth and plays a positive role in activation of the MAP kinase pathway. Putative link with downstream effectors of RET in neuronal differentiation.
Protein Families	DOK family, Type B subfamily
Research Area	Signal Transduction
Tissue Specificity	Highest expression in skeletal muscle, lower in brain, heart and kidney. Also detected in activated peripheral blood T-lymphocytes.
Weight	38.8kDa

Stotage Note	Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.
Buffer	Tris-based buffer，50% glycerol
Purity	Greater than 90% as determined by SDS-PAGE.
Storage	The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Storage Buffer	Tris-based buffer,50% glycerol

Immunogen Species	Homo Sapiens (Human)

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SKU	Supplier No.	Size	Your price	Quantity
BHP10500488	CSB-EP007111HU	1mg	$1812		Add to Cart
BHP10500488	CSB-EP007111HU	100ug	$419		Add to Cart
BHP10500488	CSB-EP007111HU	20ug	$224		Add to Cart

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