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Home / Proteins & Peptide

Recombinant Human Dickkopf-Related Protein 1/DKK-1 (C-Avi-6His) Biotinylated

SKU : BHP10304981

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Elabscience Biotechnology Co.,Ltd

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Mfr.No.	PKSH034043
Alternative Names	Dickkopf-related protein 1; Dickkopf-1; Dkk-1
Reconstitution	Please refer to the printed manual for detailed information.
Background	Dickkopf-related protein 1(DKK-1), is a member of the dickkopf family. DKK1 secreted proteins with two cysteine-rich domains separated by a linker region. It antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero-posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease.
Reactivity	Human
Tag	C-Avi-6His
Description	Biotinylated Recombinant Human Dickkopf-related protein 1 is produced by our Mammalian expression system and the target gene encoding Thr32-His266 is expressed with a Avi, 6His tag at the C-terminus.
Formulation	Lyophilized from a 0.2 um filtered solution of PBS, pH 7.4.
Host	Human Cells
Accession Number	O94907
Endotoxin Level	< 1.0 EU per ug as determined by the LAL method.
Mol Weight	28.4 kDa
Mw(kda)	28.4 kDa

Sequence Info	Thr32-His266

Shipping	This product is provided as lyophilized powder which is shipped with ice packs.
Stotage Note	Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Purity	>95% as determined by reducing SDS-PAGE.

Product Manual	Data Sheet

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SKU	Supplier No.	Size	Your price	Quantity
BHP10304981	PKSH034043	20ug	$342		Add to Cart
BHP10304981	PKSH034043	100ug	$924		Add to Cart

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