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Home / Proteins & Peptide

Recombinant Human DCX Protein (aa 45-150, GST Tag)

SKU : BHP10302774

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Elabscience Biotechnology Co.,Ltd

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Mfr.No.	PKSH030620
Description	A DNA sequence encoding the human DCX (O43602-2) N-terminal fragment (Ala 45-Val 150) was fused with the GST tag at the N-terminus.
Alternative Names	DBCN;DC;LISX;SCLH;XLIS
Reconstitution	Please refer to the printed manual for detailed information.
Background	DCX (doublecortin, N-GST chimera)contains 2 doublecortin domains and belongs to the doublecortin family. It is highly expressed in neuronal cells of fetal brain, but not expressed in other fetal tissues. In the adult, it is highly expressed in the brain frontal lobe, but very low expression in other regions of brain, and not detected in heart, placenta, lung, liver, skeletal muscles, kidney and pancreas. DCX is a microtubule-associated protein required for initial steps of neuronal dispersion and cortex lamination during cerebral cortex development. It may act by competing with the putative neuronal protein kinase DCAMKL1 in binding to a target protein. DCX may in that way participate in a signaling pathway that is crucial for neuronal interaction before and during migration, possibly as part of a calcium ion-dependent signal transduction pathway. It may be part with LIS-1 of a overlapping, but distinct, signaling pathways that promote neuronal migration. Defects in DCX are the cause of lissencephaly X-linked type 1 and subcortical band heterotopia X-linked.
Reactivity	Human
Tag	N-GST
Formulation	Lyophilized from sterile 20mM Tris, 1mM DTT, 10% glycerol, pH 7.5
Host	E.coli
Accession Number	O43602-2
Endotoxin Level	Please contact us for more information.
Mol Weight	39.4 kDa
Mw(kda)	39.4 kDa

Sequence Info	Ala 45-Val 150

Shipping	This product is provided as lyophilized powder which is shipped with ice packs.
Stotage Note	Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Purity	> 82 % as determined by reducing SDS-PAGE.

Product Manual	Data Sheet

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SKU	Supplier No.	Size	Your price	Quantity
BHP10302774	PKSH030620	50ug	$486		Add to Cart

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